Huina mole: C24H30N2O7H2O
Hiki ke hoʻohana ʻia ʻo Advantame e like me ka mea ʻono ma luna o ka papaʻaina a i loko o kekahi mau bubblegums, nā mea inu ʻono, nā huahana waiū, nā jams a me nā mea ʻono i waena o nā mea ʻē aʻe.
ʻO ka FDA e ʻae ʻia i kēlā me kēia lā o ka advantame no nā kānaka he 32.8 mg no ka kg o ke kaumaha o ke kino (mg/kg bw), aʻo ka EFSA he 5 mg i kēlā me kēia kg o ke kaumaha kino (mg/kg bw).
ʻO nā meaʻai i manaʻo ʻia i kēlā me kēia lā aia ma lalo o kēia mau pae.NOAEL no kanaka he 500 mg/kg bw ma EU.Hiki ke hana i ka advantame i loko o ka phenylalanine, akā ʻaʻole koʻikoʻi ka hoʻohana maʻamau o ka advantame i ka poʻe me ka phenylketonuria.ʻAʻohe hopena maikaʻi ʻole i ka maʻi diabetes type 2.ʻAʻole i manaʻo ʻia he carcinogenic a mutagenic paha.
Hoʻonohonoho ka Center for Science in the Public Interest i kahi kūlana palekana ma ke ʻano he palekana.